Born in 1939 in Kolkata, West Bengal, Shri Ali Ahmad Hussain Khan received his training in Shehnai from Shri Nazir Hussain Khan and Shri Imdad Hussain Khan. Later, he studied vocal music under Shri Tansen Pandey.
Shri Ali Ahmad Hussain Khan represents the Benaras school of Shehnai music and ranks high among Shehnai exponents today. A top-grade artist of All India Radio, he has performed all over the country. He has also played in concerts with leading Hindustani musicians such as Ustad Vilayat Khan, Shri Munawwar Ali Khan, and Pandit V.G. Jog besides accompanying Peter Michael Namel on the piano. Shri Ali Ahmad Hussain has produced a number of gramophone records, audio-cassettes and CDs of his music. He has been featured in History of Shehnai, a documentary produced by Doordarshan.
For his services to music, he has received several honours including the ITC Sangeet Research Academy Award in 2009. Shri Ali Ahmad Hussain Khan receives the Sangeet Natak Akademi Award for his contribution to Hindustani instrumental music.